Tibolone and the cardiovascular system

Tibolone and the endometrium - Tibolone and bleeding

The Effects of Tibolone on Risk Factors of Cardiovascular Disease in Menopausal Women

Background: Tibolone is frequently used as a hormone-like alternative to traditional HRT. Therefore, it is valuable to compare the effects of tibolone and HRT on cardiovascular diseases risk factors. Methods: A total of 156 healthy non-surgical postmenopausal women were included in an open randomized study. They were assigned to receive daily 2.5 mg tibolone plus one Cal+D (500 mg calcium and 2...

Effects of Benzimidazole derivatives on digestive system and cardiovascular system

One of the goals of medicinal chemistry research and drug discovery is to provide a rationalbasis for the design of new medicinal agents. Organic compounds and their reactions have beenutilized by people since antiquity. Due to the increasing demand for bioactive molecules, organicchemists are increasingly required to synthesize new compounds of biological interest. AsBenzimidazoles are very us...

[Effects of tibolone on the risk factors for cardiovascular diseases in postmenopausal women].

BACKGROUND/AIM Tibolone is a preparation that belongs to the group of steroidal substances. The effects of the use of the use of tibolone are the consequence of the activities of its metabolities, considering that their hormonal activity depends on the type of tissue in which they develop. The aim of this study was to evaluate the influence of the use of tibolone on risk factors for the develop...

The effect of glutaminergic system on cardiovascular regulation of rat

Introduction: The bed nucleus stria terminalis (BST) is a part of the limbic system, which plays a role in regulation of heart beat and blood circulation. It was recently shown that microinjection of L-glutamate in the BST elicits cardiovascular depressive, but the role of glutamate receptor subtypes has not been investigated yet. In this study, the role of glutamate receptor subgroups in regul...